Introduction
Advanced heart failure is a growing issue. Existing pharmacological strategies increase the survival rates of acute heart failure patients, providing a growing source of patients with advanced disease. In view of long waiting lists for heart transplantation and the growing lack of donors, cardiac resynchronization and mechanical circulatory support devices have demonstrated promising results.

Scope
What are the current definitions, diagnostic methods and treatment approaches of the early stages of the disease?

What are the main issues surrounding treatment approaches in the advanced stages of the disease?

What is the current role of cardiac resynchronization therapy in treatment of advanced heart failure?

What are the main non-pharmacological options as alternatives to heart transplantation in advanced heart failure?

Report Highlights
With no new drug therapies addressing advanced heart failure and existing pharmacological strategies failing to compensate a weakening heart, alternative, non-pharmacological solutions have to be found. In view of long waiting lists for heart transplantation and the growing shortage of donor hearts, the focus of treatment must shift onto devices.

Ventricular dyssynchrony is a well recognized problem in advanced stages of heart failure. Clinical trials investigating ventricular dyssynchrony cardiac resynchronization have demonstrated promising results. However, this technology provides only temporary, symptomatic relief and neither cures nor fully stops the progression of the disease.

In light of the growing shortage of donor hearts and failing pharmacological strategies, an artificial mechanical heart has been a long sought-after technology. Although the developments started decades ago, a fully implantable total artificial heart is still at the concept stage, with many years of research and development yet to come.

Reasons to Purchase
Understand current definitions, diagnostic methods and treatment approaches in advanced heart failure

Current dynamics and future trends of the technology developments treating advanced heart failure

Major technological and industry issues surrounding technological progress and new product development